Patheon® is a leading provider of drug substance and drug product services for the global biopharmaceutical industry. SEE AND Read More »

Want to learn more?

Patheon Overview Brochure

Lifecycle Management Services

Wherever you want to take your product next, Patheon can get you there.

With fully integrated services and the experience of more than 50 successful lifecycle management projects, Patheon can quickly and cost-effectively take your compound from preformulation to large-scale manufacturing.

Patheon can help you make the most of your investment by maximizing the life and reach of your product:

Improve Solubility: Resolving solubility issues can often unlock the potential for a much-improved formulation and dosage form.
Enhance Clinical Benefits: Modified release dosage forms can improve patient compliance and enhance clinical benefits.
Patent Extension: Reformulating for another market or condition, or offering a new dose form or strength, are effective ways to maintain exclusivity.
Synergistic Combinations: By combining your API with other drugs you can create a new product to simplify patient compliance or address unmet clinical needs.

Unlike other companies that are tied to a proprietary technology, Patheon gives you royalty-free access to a broad range of dose forms, formulation methods and technologies:

Sustained Release: Coated tablets, laser-drilled osmotic tablets, matrix systems
Immediate Release: Fast dispersible, sublingual and buccal tablets
Multi-Therapy: Bilayer, trilayer, and bilayer chewable tablets, capsules
Solubilization: Scalable technologies to improve bioavailability
Taste Masking: Palatable formulation of oral liquids, chewable and fast dispersible tablets
Lyophilization & Sterile Liquid: Vials, prefilled Syringes and cartridges

Case Study: Continued Success with Lifecycle Management Services

The Challenge A marketed adult tablet was reported to have an extremely bad taste and after taste. The customer came to Patheon for taste masking to improve patient compliance, and explore line extension into the pediatric market.

The Solution Several techniques such as tablet coating, multilayer polymer coating, multiparticulate systems were evaluated. Particle coating with taste masking agents and compression of multiparticulates into a tablet was found to be the most promising approach. A custom bitter masking system was developed by flavor optimization specialists utilizing taste panels.

The Outcome The improved taste-masked product opened the door to a patent extension and exclusivity in the pediatric market.

Ask The Experts

Ann Newman, Ph.D.

Ann Newman, Ph.D.
Dr. Newman’s expertise is in solid-state chemistry: physical forms, polymorphism, salts, cocrystals,
Read More »

Anil Kane, Ph.D., MBA

Anil Kane, Ph.D., MBA
Dr. Kane has more than 25 years of experience in the science and business of taking molecules throug
Read More »

Robert A. Lipper, Ph.D.

Robert A. Lipper, Ph.D.
Having ushered multiple products to market though the entire development process, Dr. Lipper is an e
Read More »

Joseph A. Fix, MBA, Ph.D.

Joseph A. Fix, MBA, Ph.D.
With 30 years of experience converting discoveries into businesses, Dr. Fix holds 24 patents, includ
Read More »

K. George Mooney, Ph.D.

K. George Mooney, Ph.D.
Dr. Mooney has 35 years’ experience in pharmaceutical sciences and exploratory drug development. He
Read More »

Rodney Pearlman, PhD.

Rodney Pearlman, PhD.
An expert in the development of scientific and business strategies for start-ups, Dr. Pearlman bring
Read More »

Giuseppe Cassisi, MBA

Giuseppe Cassisi, MBA
With a solid foundation of marketing and sales, and expertise in the licensing of generics and drug
Read More »

View All »

Knowledge Library


Please fill the below form to access requested content

First Name

Last Name

Company

Title

Email

Phone

Address Line 1

Address Line 2

City

Zip/ Postal Code

Country

Submit