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Predicting drug loading limits in tablet formulations

Reducing formulation iteration cycles

Limited early insight into formulation performance can lead to repeated development cycles, extending timelines and increasing resource demands.

Case study overview

In this case study, early modeling through the OSDPredict™ platform was used to provide insight into formulation behavior for a customer addressing this challenge, reducing iteration cycles downstream. This approach helped to streamline development and improve efficiency in the early stages.

Using the OSDPredict™ platform, the team was able to:

  • Predict drug loading limits based on formulation composition and material properties 
  • Evaluate the impact of excipients and process parameters on tablet performance 
  • Identify potential risks early in development 
  • Reduce the need for iterative formulation cycles

Key outcomes of drug loading limits identification

  • Reduced formulation iteration cycles and development timelines 
  • Improved understanding of formulation performance early in development 
  • Increased efficiency in formulation design and optimization 
  • More confident decision-making for tablet development
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