Global clinical packaging services
Primary packaging, secondary packaging and labeling, and pre-filled syringe assembly solutions and services
Ensuring investigational medicinal product (IMP) integrity, advancing medication adherence, and avoiding delays in trial timelines are all top of mind for biotechnology and pharmaceutical companies embarking on the clinical trial journey.
Thermo Fisher Scientific pharma services offer global clinical packaging capabilities — which include fully-owned cGMP facilities, patient-centric packaging solutions, and efficient processes and time saving tools — to help prevent potential holdups along the way.
Our facilities support ambient, refrigerated, and frozen packaging capabilities, and are strategically located around the globe to accommodate regional needs. An integrated IT system links the facilities to give clients control over inventory via bar code standards.
Capabilities
Primary packaging
- Coldform/Thermoform blistering lines in temperature- and humidity-monitored rooms
- In-house tooling creation, on-line printing, and in-process vision control systems
- Single and multi-pack capabilities
- Automation that reduces cycle times and containment suites that handle potent or powder compounds with independent engineering resources
- Automated and manual bottling services
Secondary packaging and labeling
- Range of package types including child-resistant blister cards and bottles, vials, patches, syringes, inhalers, and other devices
- Manual or automated pack and assembly in rooms with managed temperature requirements
- Label design, translations, and blinding for single-panel and multi-panel, as well as 1-3 panel booklet labels and digital labels
ProSyriesSM pre-filled syringe packaging and labeling
- Precision-controlled syringe that’s assembled and labeled using a fully automated, temperature-controlled, continuous process
- Automated production lines available in both ambient and cold environments
- OCR-OCV controls and integrated quality processes ensure 100% inspection of variable and fixed text for accuracy and legibility
- ProSyries Syringe Tray, designed to prevent stopper/plunger movement during air transit
- ProSyries High Precision Syringe Labeling is available for any fill level of pre-filled syringes with +/-0.5MM accuracy
Smart packaging (medication adherence solutions)
Smart packaging uses microcircuits to passively measure dosing data and connects to the cloud through technology such as the patient’s smartphone. Cloud-based platforms then use sophisticated algorithms to analyze patient dosing behaviors and flag anything erratic, so site staff can “rescue” patients and get them back on their appropriate regimen.
Smart packaging for medication adherence provides a rich and reliable data set to help better understand patient dosing — making it applicable to most clinical trial designs. It’s especially useful for clinical trials that:
- Require a precise understanding of time between doses
- Have complex dosing regimens
- Last longer than one year
- Include long inter-visit periods to clinical sites (decentralized clinical trials)
Allentown is our largest ambient and cold packaging, storage and distribution facility for clinical trials.
The site has expanded services to include commercial packaging with serialization, offering primary packaging of oral solid dose for blister packs & bottles, with additional secondary packaging services for syringe / pre-filled syringe / pen / autoinjector assembly and labeling.
Our facility in Mount Prospect, Illinois provides a full suite of clinical supply chain capabilities and solutions from primary and secondary packaging through domestic and international distribution for your ambient/controlled room temperature and cold chain needs.
Our Horsham facility provides automated global distribution and integrated biologic product capabilities.
Comprehensive service lines supporting all aspects of clinical trial supply—primary & secondary packaging, labeling, regulatory support, distribution, returns and destruction.
Our Basel, Switzerland site offers Comprehensive service line supporting all aspects of clinical trial supply—primary & secondary packaging, labeling, regulatory support, distribution, returns and destruction, and comparator sourcing. Additionally the site supports cold chain supplies management and has In-house engineering capabilities for tooling, equipment customization, production automation.
Strategically located in a Free Trade Zone, clinical trial sponsors can realize significant cash flow advantages as there are zero duty and VAT payments imposed on shipments entering Suzhou. Capabilities include Primary and secondary packaging at ambient and refrigerated temperatures, with support for high-potent compound and light-sensitive packaging, in house global labeling service, clinical manufacturing, Clinical ancillary management, pick & pack and distribution services, GMP temperature & RH-controlled storage at ambient (10°C to 20°C and 15°C to 25°C), refrigerated (2°C to 8°C) and frozen (-20°C)
Helpful Resources
eBook
Clinical Trial Packaging: Innovative, Flexible and Time-Sensitive Solutions
Clinical trial packaging solutions can be as diverse as the medications they protect. Learn how our clinical study sponsors were able to implement a packaging design that scaled through all phases of the trial while reducing time and waste.
View eBook
Fact Sheet
Global packaging solutions
Leveraging over 30 years of global clinical packaging and labeling expertise, Thermo Fisher Scientific offers flexible clinical supply services that can help streamline and add speed to your packaging and labeling workflow.
View Fact Sheet
Fact Sheet
Smart Packaging – Gain Confidence in Clinical Trial Outcomes
Smart Packaging – Gain Confidence in Clinical Trial Outcomes Evaluating and onboarding new vendors to implement a new technology can be daunting. The team at Patheon pharma services has...
View Fact Sheet
Blog
Adherence and Accuracy: Smart packaging advances the quality imperative in clinical trials
Learn from Thermo Fisher Scientific’s head of medication adherence and biomarker measurement about data-quality implications of smart packaging and how to integrate them into clinical trials.
Read Blog