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ZTTK-iPSC: A framework for the rapid generation of patient-specific rare disease cell models

Poster

This poster describes the first successful iPSC generation of ZTTK cells from a 2-year-old patient, as well as the establishment of optimal single cell cloning and gene editing parameters for future experiments.

Author(s):
Rachel Koenigsberg1,2
Colleen Richards1
Intisar Turner1
Chad C. MacArthur1
Terry J. Bichell3
Erin E. Ahn4
Uma Lakshmipathy1
1 Pharma Services, Thermo Fisher Scientific, San Diego, CA, USA
2 Biological Sciences, California Polytechnic State University, San Luis Obispo, CA, USA
3 COMBINEDBrain, Brentwood, TN, USA
4 Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA
Framework for Rapid iPSC Generation of ZTTK Cells