Achieving optimal bioavailability of active pharmaceutical ingredients (APIs) is essential for therapeutic success. Lipid formulations have emerged as a key solution, particularly via softgel capsules. These formulations leverage the body’s natural digestive processes in the gastrointestinal (GI) tract to enhance API absorption. They can also promote lymphatic transport, which is especially beneficial for poorly soluble drugs with high first-pass metabolism, such as hormones and other therapeutic agents.
This on-demand webinar, featuring industry-leading insights from two Thermo Fisher Scientific experts in softgel technology, explores how lipid formulations can enhance drug absorption and bioavailability. It also examines the various types of lipid systems—such as solutions, suspensions, emulsions, and self-(micro)emulsifying formulations—and their applications across therapeutic areas, including HIV, oncology, immunosuppressants, and emerging treatments such as medicinal cannabis (e.g., CBD).
Key takeaways include:
The lipid formulation development process, including screening tools used to optimize formulations
Critical steps in scaling up and industrializing lipid-based systems for consistent, efficient production
How lipid formulations in softgels can transform drug delivery, as well as enhance patient outcomes