The vice president of manufacturing for a clinical-stage biopharmaceutical company faced an avalanche of work when a reorganization left him without a clinical supply manager. Planning to start 5 new clinical trials in 6 months while managing quality assurance, manufacturing, and supplies for new and ongoing studies, he turned to his Thermo Fisher Scientific account executive with a simple question: “How am I going to do all that?” Read this case study to learn how with proper controls, operating procedures, and training in place, the Clinical Supply Optimization team adopted the new duties in addition to planning, forecasting and inventory management tasks.