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There are many parenteral dosage forms from which the pharmaceutical scientist can choose to develop their drug product. For primary pack choices, there are traditional vials, ampoules, cartridges, pre-filled syringes and complex containers such as the various types of dual chamber syringes. Additionally, there are newer dosage forms such as wearable injection devices or pump patches. Each have their own merits and advantages, but these advantages may not be realized until the product is marketed. Consideration must also be made on the form of the product within the container and the environment in which it will be used and needs to be (or is able to be) stored.
To make the right choices which can, and arguably should, change during the development life cycle of the product, the pharmaceutical scientist needs to employ a sound development strategy.
Author: Tony Pidgeon, Process Technology Director, Pharma Services, Patheon, by Thermo Fisher Scientific