Strategies for API Solubility and Bioavailability Enhancement


The landscape of today’s drug development industry looks far different than it did only a decade ago. Innovation is creating exciting new possibilities in patient care. Improvements in synthetic chemistry and high-throughput screening have opened up the small molecule chemical space, leading to novel compounds with the desirable potency. However, they also come with greater solubility challenges. Download this whitepaper to learn why it is critical that formulation scientists use the most appropriate solubility enhancement technology and formulation strategies to improve the bioavailability of poorly soluble drugs.

Authors: Sanjay Konagurthu, Ph.D., Senior Director, Pharma Services Group, Thermo Fisher Scientific Tom Reynolds, Principal Scientist, Pharma Services Group, Thermo Fisher Scientific