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Gosselies, Belgium, Europe

Viral vector development and analytical facility

Gosselies, Belgium, Europe

Thermo Fisher Scientific’s Gosselies facility, located in the heart of Belgium’s largest biotech hub, is dedicated to developing viral vectors (process and analytical) for clinical applications.

The facility has 400 square meters of R&D space, and 380 square meters of classified cGMP space staffed by industry experts in the development of viral vectors, viruses, vaccines, and other therapies. The facility ensures a lean and efficient transfer from viral vector development to cGMP manufacturing.

Gosselies is part of our European network of viral vector sites, which includes Seneffe, Belgium, and part of our global network, including Cambridge, Lexington and Plainville, MA in the US.

Location Image

16 rue Clément Ader,
6041 Gosselies,
Belgium 
Tel: +32 71 347900

Viral vector manufacturing and development capabilities at Plainville facility

Key Capabilities:

  • Experience in viral vector and virus development for cell and gene therapies, vaccine applications and other therapies.
  • Process and analytical development
  • Broad array of adherent and suspension processes
  • Small- to mid-scale: up to 200L
Facility Offering
Specifications
Process Development
  • Upstream DOE studies in ambr 250
  • 200L pilot bioreactor and Cell Stack 10
  • Hyperstack36 adherent process – preclinical
  • production and scale-up
  • Clarification optimization
  • Depth and other filtration methods
  • TFF concentration and buffer exchange
  • Varied Chromatography modalities/resins: Affinity, SEC, IEX, HIC, etc.
  • Viral inactivation/clearance support
  • Centrifugal separations
  • Scale down process and Process Characterization
  • Process Characterization
     
  • Process Scale down, process design and process characterization
  • Process Development
  • Assay establishment, customization and/or development
  • Activity, purity, product quality and yield (DOE) - Qualification & validation of methods
  • DOE and Pre-clinical material testing -Transfer to QC for testing
  • To learn more about this location, download the site capabilities factsheet.

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